Research

An overview of my scientific publications.

  • 2024

    Improving assessment of lesions in longitudinal CT scans: a bi-institutional reader study on an AI-assisted registration and volumetric segmentation workflow

    Alessa Hering,Max Westphal,Annika Gerken,Haidara Almansour,Michael Maurer,Benjamin Geisler,Temke Kohlbrandt,Thomas Eigentler,Teresa Amaral,Nikolas Lessmann,Sergios Gatidis,Horst Hahn,Konstantin Nikolaou,Ahmed Othman,Jan Moltz,Felix Peisen

    reader study
    Bayesian statistics
    GLMM
    artificial intelligence
    segmentation

    Journal article | International Journal of Computer Assisted Radiology and Surgery | '10.1007/s11548-024-03181-4'


    Citation:

    Hering, Alessa, et al. "Improving assessment of lesions in longitudinal CT scans: a bi-institutional reader study on an AI-assisted registration and volumetric segmentation workflow." International Journal of Computer Assisted Radiology and Surgery 19.9 (2024): 1689-1697.

  • 2024

    Statistical inference for diagnostic test accuracy studies with multiple comparisons

    Max Westphal,Antonia Zapf

    multiplicity
    co-primary endpoints
    sensitivity
    specificity

    Journal article | Statistical Methods in Medical Research | '10.1177/09622802241236933'


    Citation:

    Westphal, Max, and Antonia Zapf. "Statistical inference for diagnostic test accuracy studies with multiple comparisons." Statistical Methods in Medical Research 33.4 (2024): 669-680.

  • 2024

    Models for the marrow: A comprehensive review of AI-based cell classification methods and malignancy detection in bone marrow aspirate smears

    Tabita Ghete,Farina Kock,Martina Pontones,David Pfrang,Max Westphal,Henning Höfener,Markus Metzler

    bone marrow
    review
    artificial intelligence
    cell classification
    diagnosis

    Journal article | HemaSphere | '10.1002/hem3.70048'


    Citation:

    Ghete, Tabita, et al. "Models for the marrow: A comprehensive review of AI‐based cel l classification methods and malignancy detection in bone marrow aspirate smears." HemaSphere 8.12 (2024): e70048.

  • 2023

    Machine learning algorithm improves the detection of NASH (NAS-based) and at-risk NASH: A development and validation study

    Jenny Lee,Max Westphal,Yasaman Vali,Jerome Boursier,Salvatorre Petta,Rachel Ostroff,Leigh Alexander,Yu Chen,Celine Fournier,Andreas Geier,Sven Francque,Kristy Wonders,Dina Tiniakos,Pierre Bedossa,Mike Allison,Georgios Papatheodoridis,Helena Cortez-Pinto,Raluca Pais,Jean-Francois Dufour,Diana Julie Leeming,Stephen Harrison,Jeremy Cobbold,Adriaan G. Holleboom,Hannele Yki-Järvinen,Javier Crespo,Mattias Ekstedt,Guruprasad P. Aithal,Elisabetta Bugianesi,Manuel Romero-Gomez,Richard Torstenson,Morten Karsdal,Carla Yunis,Jörn M. Schattenberg,Detlef Schuppan,Vlad Ratziu,Clifford Brass,Kevin Duffin,Koos Zwinderman,Michael Pavlides,Quentin M. Anstee,Patrick M. Bossuyt

    nonalcoholic steatohepatitis
    nonalcoholic fatty liver disease
    risk prediction
    machine learning
    model development
    validation

    Journal article | Hepatology | '10.1097/HEP.0000000000000364'


    Citation:

    Lee, Jenny, et al. "Machine learning algorithm improves the detection of NASH (NAS-based) and at-risk NASH: A development and validation study." Hepatology 78.1 (2023): 258-271.

  • 2023

    Evaluation of the EsteR toolkit for COVID-19 decision support: sensitivity analysis and usability study

    Rieke Alpers,Lisa Kühne,Hong-Phuc Truong,Hajo Zeeb,Max Westphal,Sonja Jäckle

    covid-19
    decision support
    statistical modelling
    evaluation
    usability

    Journal article | JMIR Formative Research | '10.2196/44549'


    Citation:

    Alpers, Rieke, et al. "Evaluation of the EsteR toolkit for COVID-19 decision support: sensitivity analysis and usability study." JMIR formative research 7 (2023): e44549.

  • 2022

    Recommendations on compiling test datasets for evaluating artificial intelligence solutions in pathology

    André Homeyer,Christian Geißler,Lars Ole Schwen,Falk Zakrzewski,Theodore Evans,Klaus Strohmenger,Max Westphal,Roman David Bülow,Michaela Kargl,Aray Karjauv,Isidre Munné-Bertran,Carl Orge Retzlaff,Adrià Romero-López,Tomasz Sołtysiński,Markus Plass,Rita Carvalho,Peter Steinbach,Yu-Chia Lan,Nassim Bouteldja,David Haber,Mateo Rojas-Carulla,Alireza Vafaei Sadr,Matthias Kraft,Daniel Krüger,Rutger Fick,Tobias Lang,Peter Boor,Heimo Müller,Peter Hufnagl,Norman Zerbe

    machine learning
    evaluation
    test data
    study design

    Journal article | Modern Pathology | '10.1038/s41379-022-01147-y'


    Citation:

    Homeyer, André, et al. "Recommendations on compiling test datasets for evaluating artificial intelligence solutions in pathology." Modern Pathology 35.12 (2022): 1759-1769.

  • 2022

    A multiple testing framework for diagnostic accuracy studies with co‐primary endpoints

    Max Westphal,Antonia Zapf,Werner Brannath

    diagnostic accuracy
    prediction model
    evaluation
    multiple comparisons
    co-primary endpoints

    Journal article | Statistics in Medicine | '10.1002/sim.9308'


    Citation:

    Westphal, Max, Antonia Zapf, and Werner Brannath. "A multiple testing framework for diagnostic accuracy studies with co‐primary endpoints." Statistics in medicine 41.5 (2022): 891-909.

  • 2021

    A statistical model to assess risk for supporting COVID-19 quarantine decisions

    Sonja Jäckle,Elias Röger,Volker Dicken,Benjamin Geisler,Jakob Schumacher,Max Westphal

    covid-19
    quarantine
    statistical modelling
    risk prection
    decision support

    Journal article | International Journal of Environmental Research and Public Health | '10.3390/ijerph18179166'


    Citation:

    Jäckle S, Röger E, Dicken V, Geisler B, Schumacher J, Westphal M. A Statistical Model to Assess Risk for Supporting COVID-19 Quarantine Decisions. International Journal of Environmental Research and Public Health. 2021; 18(17):9166. https://doi.org/10.3390/ijerph18179166

  • 2020

    Model Selection and Evaluation in Supervised Machine Learning

    Max Westphal

    machine learning
    prediction model
    model selection
    evaluation
    multiple comparisons

    Doctoral dissertation | Universität Bremen | '10.26092/elib/16'


    Citation:

    Westphal, Max. Model Selection and Evaluation in Supervised Machine Learning. Diss. Universität Bremen, 2020.

  • 2020

    Evaluation of multiple prediction models: A novel view on model selection and performance assessment

    Max Westphal,Werner Brannath

    machine learning
    prediction model
    evaluation
    multiple comparisons

    Journal article | Statistical methods in medical research | '10.1177/0962280219854487'


    Citation:

    Westphal M, Brannath W. Evaluation of multiple prediction models: A novel view on model selection and performance assessment. Statistical Methods in Medical Research. 2019;29(6):1728-1745.

  • 2019

    Improving model selection by employing the test data

    Max Westphal

    machine learning
    model selection
    multiple testing

    Conference article | International Conference on Machine Learning | ''


    Citation:

    Westphal, Max, and Werner Brannath. "Improving model selection by employing the test data." International Conference on Machine Learning. PMLR, 2019.

  • 2019

    Simultaneous inference for multiple proportions: a multivariate beta-binomial model

    Max Westphal

    Bayesian statistics
    beta-binomial model
    binary data
    credible regions

    Preprint | arXiv | '10.48550/arXiv.1911.00098'


    Citation:

    Westphal, Max. "Simultaneous inference for multiple proportions: a multivariate beta-binomial model." arXiv preprint arXiv:1911.00098 (2019).

  • 2017

    CT at onset of chronic lung allograft dysfunction in lung transplant patients predicts development of the restrictive phenotype and survival

    Sabine Dettmer,Hoen-oh Shin,Jens Vogel-Claussen,Max Westphal,Axel Haverich,Gregor Warnecke,Tobias Welte,Frank Wacker,Jens Gottlieb,Hendrik Suhling

    chronic lung allograft dysfunction
    risk prediction
    model development

    Journal article | European Journal of Radiology | '10.1016/j.ejrad.2017.06.008'


    Citation:

    CT at onset of chronic lung allograft dysfunction in lung transplant patients predicts development of the restrictive phenotype and survival Dettmer, Sabine et al. European Journal of Radiology, Volume 94, 78 - 84

  • 2017

    Transition from pediatric to adult medical care – a survey in young persons with inflammatory bowel disease

    Antje Timmer,Jenny Peplies,Max Westphal,Birgit Kaltz,Antje Ballauff,Martin Claßen,Martin W Laass,Sibylle Koletzko

    inflammatory bowel disease
    survey
    multinomial logistic regression

    Journal article | PLoS One | '10.1371/journal.pone.0177757'


    Citation:

    Timmer A, Peplies J, Westphal M, Kaltz B, Ballauff A, Claßen M, et al. (2017) Transition from pediatric to adult medical care – A survey in young persons with inflammatory bowel disease. PLoS ONE 12(5): e0177757. https://doi.org/10.1371/journal.pone.0177757

  • 2017

    Antiviral treatment and liver‐related complications in hepatitis delta

    Anika Wranke,Beatriz Calle Serrano,Benjamin Heidrich,Janina Kirschner,Birgit Bremer,Patrick Lehmann,Svenja Hardtke,Katja Deterding,Kerstin Port,Max Westphal,Michael P Manns,Markus Cornberg,Heiner Wedemeyer

    hepatitis delta
    observational study
    survival analysis

    Journal article | Hepatology | '10.1002/hep.28876'


    Citation:

    Wranke, Anika, et al. "Antiviral treatment and liver‐related complications in hepatitis delta." Hepatology 65.2 (2017): 414-425

  • 2017

    Non‐invasive fibrosis score for hepatitis delta

    Gunnar L Lutterkort,Anika Wranke,Cihan Yurdaydin,Eva Budde,Max Westphal,Ralf Lichtinghagen,Judith Stift,Birgit Bremer,Svenja Hardtke,Onur Keskin,Ramazan Idilman,Armin Koch,Michael P Manns,Hans P Dienes,Heiner Wedemeyer,Benjamin Heidrich

    fibrosis
    risk prediction
    diagnosis
    model development

    Journal article | Liver International | '10.1002/hep.28876'


    Citation:

    Wranke, Anika; Serrano, Beatriz Calle; Heidrich, Benjamin; Kirschner, Janina; Bremer, Birgit; Lehmann, Patrick; Hardtke, Svenja; Deterding, Katja1; Port, Kerstin; Westphal, Max; Manns, Michael P.; Cornberg, Markus; Wedemeyer, Heiner. Antiviral treatment and liver‐related complications in hepatitis delta. Hepatology 65(2):p 414-425, February 2017. | DOI: 10.1002/hep.28876

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